Question

What are lipid rafts and explain?

Answer 1

Lipid rafts are subdomains of the plasma membrane that contain high concentrations of cholesterol and glycosphingolipids. They exist as distinct liquid-ordered regions of the membrane that are resistant to extraction with nonionic detergents.

Answer 2

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• Lipid rafts are plasma membrane microdomains enriched in cholesterol and sphingolipids that are involved in the lateral compartmentalization of molecules at the cell surface.
• Internalization of ligands and receptors by these domains occurs via a process defined as raft-dependent endocytosis.