What are lysosomes? what types of molecules would be found?
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The lysosomes also act as the waste disposal system of the cell by digesting unwanted materials in the cytoplasm, both from outside the cell and obsolete components inside the cell. Material from outside the cell is taken-up throughendocytosis, while material from the inside of the cell is digested throughautophagy. Their sizes can be very different—the biggest ones can be more than 10 times bigger than the smallest ones.They were discovered and named by Belgian biologist Christian de Duve, who eventually received the Nobel Prize in Physiology or Medicine in 1974.
Lysosomes are known to contain more than 60 different enzymes.Enzymes of the lysosomes are synthesised in therough endoplasmic reticulum. The enzymes are imported from the Golgi apparatus in small vesicles, which fuse with larger acidic vesicles. Enzymes destined for a lysosome are specifically tagged with the molecule mannose 6-phosphate, so that they are properly sorted into acidified vesicles.
Synthesis of lysosomal enzymes is controlled by nuclear genes. Mutationsin the genes for these enzymes are responsible for more than 30 different human genetic disorders, which are collectively known as lysosomal storage diseases. These diseases result from an accumulation of specific substrates, due to the inability to break them down. These genetic defects are related to several neurodegenerative disorders, cancer, cardiovascular diseases, andageing-related diseases.
Lysosomes should not be confused withliposomes, or with micelles.
The lysosomes also act as the waste disposal system of the cell by digesting unwanted materials in the cytoplasm, both from outside the cell and obsolete components inside the cell. Material from outside the cell is taken-up throughendocytosis, while material from the inside of the cell is digested throughautophagy. Their sizes can be very different—the biggest ones can be more than 10 times bigger than the smallest ones.They were discovered and named by Belgian biologist Christian de Duve, who eventually received the Nobel Prize in Physiology or Medicine in 1974.
Lysosomes are known to contain more than 60 different enzymes.Enzymes of the lysosomes are synthesised in therough endoplasmic reticulum. The enzymes are imported from the Golgi apparatus in small vesicles, which fuse with larger acidic vesicles. Enzymes destined for a lysosome are specifically tagged with the molecule mannose 6-phosphate, so that they are properly sorted into acidified vesicles.
Synthesis of lysosomal enzymes is controlled by nuclear genes. Mutationsin the genes for these enzymes are responsible for more than 30 different human genetic disorders, which are collectively known as lysosomal storage diseases. These diseases result from an accumulation of specific substrates, due to the inability to break them down. These genetic defects are related to several neurodegenerative disorders, cancer, cardiovascular diseases, andageing-related diseases.
Lysosomes should not be confused withliposomes, or with micelles.
I hope it is right
Lysosomes are known to contain more than 60 different enzymes.Enzymes of the lysosomes are synthesised in therough endoplasmic reticulum. The enzymes are imported from the Golgi apparatus in small vesicles, which fuse with larger acidic vesicles. Enzymes destined for a lysosome are specifically tagged with the molecule mannose 6-phosphate, so that they are properly sorted into acidified vesicles.
Synthesis of lysosomal enzymes is controlled by nuclear genes. Mutationsin the genes for these enzymes are responsible for more than 30 different human genetic disorders, which are collectively known as lysosomal storage diseases. These diseases result from an accumulation of specific substrates, due to the inability to break them down. These genetic defects are related to several neurodegenerative disorders, cancer, cardiovascular diseases, andageing-related diseases.
Lysosomes should not be confused withliposomes, or with micelles.
The lysosomes also act as the waste disposal system of the cell by digesting unwanted materials in the cytoplasm, both from outside the cell and obsolete components inside the cell. Material from outside the cell is taken-up throughendocytosis, while material from the inside of the cell is digested throughautophagy. Their sizes can be very different—the biggest ones can be more than 10 times bigger than the smallest ones.They were discovered and named by Belgian biologist Christian de Duve, who eventually received the Nobel Prize in Physiology or Medicine in 1974.
Lysosomes are known to contain more than 60 different enzymes.Enzymes of the lysosomes are synthesised in therough endoplasmic reticulum. The enzymes are imported from the Golgi apparatus in small vesicles, which fuse with larger acidic vesicles. Enzymes destined for a lysosome are specifically tagged with the molecule mannose 6-phosphate, so that they are properly sorted into acidified vesicles.
Synthesis of lysosomal enzymes is controlled by nuclear genes. Mutationsin the genes for these enzymes are responsible for more than 30 different human genetic disorders, which are collectively known as lysosomal storage diseases. These diseases result from an accumulation of specific substrates, due to the inability to break them down. These genetic defects are related to several neurodegenerative disorders, cancer, cardiovascular diseases, andageing-related diseases.
Lysosomes should not be confused withliposomes, or with micelles.
I hope it is right
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If there were no lysosomes in the cell, it will not be able to digest food and there would be accumulation of wastes like worn out parts inside the cell. Thus, cell will not be able to survive. Lysosome (also called suicide sacs) have proteins that break down waste
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