Question

What are primary lysosomes?​

Answer 1

Primary lysosomes (arrow, micrograph 1) are homogeneous, dense, membrane-bound organelles packed with acid hydrolases capable of breaking down polymers of all types. The low pH required for hydrolase activity (below pH 5) is maintained by a membrane ATP-dependent hydrogen ion pump.

Answer 2

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Primary lysosomes are the small vesicles released from the Golgi apparatus. Generally, they contain acid hydrolases or hydrolytic enzymes in the inactive form. Moreover, the content of the primary lysosomes is surrounded by a single phospholipid layer.