What are secondary Lymphoid Organs
Answers
Secondary lymphoid organs (SLOs) include lymph nodes (LNs), spleen, Peyer's patches (PPs) and mucosal tissues- the nasal associated lymphoid tissue (NALT), adenoids, and tonsils.
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➡Secondary lymphoid organs (SLOs) include lymph nodes (LNs), spleen, Peyer’s patches (PPs) and mucosal tissues- the nasal associated lymphoid tissue (NALT), adenoids, and tonsils.
➡ Less discretely anatomically defined cellular accumulations include the bronchus associated lymphoid tissue (BALT), cryptopatches, and isolated lymphoid follicles (ILFs).
➡ All SLOs serve to generate immune responses and tolerance
➡SLO development depends on the precisely regulated expression of cooperating lymphoid chemokines and cytokines LTα, LTβ, RANKL, TNF, IL-7, and perhaps IL-17.
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