What are the different stages for the preparation of vaccine ?
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- Poliomyelitis, a viral disease, has the potential to damage the central nervous system and leave children paralyzed. Jonas Salk developed an attenuated vaccine to combat the rising prevalence of the disease around the world.
- In 1955 the results from the preliminary trial of Salk’s vaccine were announced to the general public and within 2 hours it was licensed.
- Due to a lack of regulations on pharmaceutical manufacturers the vaccine was not always as pure as possible or done correctly to prevent adverse effects associated with inserting an attenuated virus into a healthy person.
- The famous Cutter Incident resulted in many recipients of the defective polio virus from the Cutter company contracting a virulent strain of polio causing paralysis. Vaccine trials and manufacturing must be handled with extreme caution to avoid infecting recipients or causing adverse effects.
- The public has not returned to the same confidence level in science and vaccines since the Cutter Incident, which risks public health for everyone.
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To permission
animal trail
clinical trials
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