What are the factors that oppose blood clotting?
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Identify factors that oppose blood clotting. Do the same for factors that hasten blood clotting. Blood clotting is made possible by plasma proteins and cell fragments called platelets (thrombocytes). Thromboplastin liberated from platelets is essential for clotting.
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Natural inhibitors of clotting factors include antithrombin III, protein S, and protein C. When activated, these proteins inactivate specific clotting factors, providing a regulatory mechanism that serves to control the coagulation response and limit the extension of the clot.
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