What are the risks and benefits of taking anti-depressants for bipolar depression?
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Answer:
- Antidepressants are an option to treat bipolar disorder, but they aren't usually the only medicine used.
- They're mostly prescribed with other medications, such as a mood stabilizer or antipsychotic.
- This can prevent manic episodes and help people better control their moods.
Risks:
- Antidepressants can trigger mania in people with bipolar disorder.
- If antidepressants are used at all, they should be combined with a mood stabilizer such as lithium or valproic acid.
- Taking an antidepressant without a mood stabilizer is likely to trigger a manic episode.
- Antidepressants can increase mood cycling.
- Antidepressants are best avoided or used with a mood stabilizer as a last resort in bipolar II
- Antidepressants should almost always be avoided in bipolar II because of the risk of hypomania and cycling
Benefits :
- Treating bipolar depression with antidepressants remains a popular option in clinical practice and published guidelines.
- Most clinicians choose the drug or class of drugs, usually selective serotonin reuptake inhibitors and bupropion, that is most effective and best tolerated.
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