Question

What are the risks of haploidy

Answer 1

Answer:

The Haplotype-relative-risk (HRR) method is a family-based method for determining gene allele association to a disease in the presence of actual genetic linkage. Nuclear families with one affected child are sampled using the parental haplotypes not transmitted as a control. While similar to the genotype relative risk (RR), the HRR provides a solution to the problem of population stratification by only sampling within family trios. The HRR method was first proposed by Rubinstein in 1981 then detailed in 1987 by Rubinstein and Falk[1] and is an important tool in genetic association studies.