What are the stop codons??
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There are three stop codons availabe which stop the process of translatio
UAA
UAG
UGA
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Stop codons have different efficiencies of termination (UAA>UAG>UGA) and in the first, and possibly the second, nucleotide 3′ of the stop codon acts as an important efficiency determinant (Stansfield et al., 1995). It can be seen from Table 6.8 that either amber (UAG) or opal (UGA) stop codons are read through; there are no examples of readthrough of the natural ochre (UAA) stop codon. However, when the suppressible UAG codon of TMV is replaced by a UAA codon, the virus can still replicate and produce mature virions (Ishikawa et al., 1986).
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