Chemistry, asked by likhith94091, 12 hours ago

What causes alkylation of DNA?

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Answered by VanshGopalOjha

Answer:

Alkylation lesions in DNA and RNA result from endogenous compounds, environmental agents and alkylating drugs. Simple methylating agents, e.g. methylnitrosourea, tobacco-specific nitrosamines and drugs like temozolomide or streptozotocin, form adducts at N- and O-atoms in DNA bases.

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