Question

What causes the change in shapeRBC from biconcave disc to elongated sickle like structure

Answer 1

Answer:

It is due to the point mutation in the beta chain of haemoglobin.for more explanation ask the same question again ..bye

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Answer 2

The mutant hemoglobin molecule undergoes polymerisation underlow oxygen tension causing the change in the shape of the rbc from biconcave disc to elongated sickle like structure.

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