Question

what do mean by negative mechanism regulates the hormone secretion

Answer 1

he feedback mechanism of hormones is the mechanism through which the balance of hormone in the blood/body is maintained. The increase or decrease in the concentration of that hormone can either stimulate the secretion of that particular hormone or inhibit the hormone secretion. This is called feedback.

There can be two type of feedback. One is called Positive feedback, and other is called negative feedback. The positive feedback stimulates the secretion or production of the hormone. On the counterpart, the negative feedback inhibits the secretion of the hormone.

For Example,

When we eat carbohydrate rich food, the glucose level in the blood increase. As the Blood Glucose level rise, the pancreas will secrete Insulin. This Insulin will signal the cells to take up the blood glucose. Hence The glucose level decrease in the blood. Now, if the insulin is still present in the blood, then more and more glucose will be transported inside the cell, and there would be a scarcity of the glucose in the blood. Hence to prevent this, negative feedback is generated due to low glucose level which would inhibit the insulin secretion in the blood.