What do you mean by displacement value. Mention its significance and how can it be determined.
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The displacement value of a drug is the number of parts by weight of drug which displaces (occupies the same volume of) 1 part by weight of the base. Displacement values refer to values for theobroma oil. These values can also be used for other fatty bases.
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Displacement Value:-
- It can be defined as the volume of drug that displaces 1 gram of suppository base.
- The most commonly used suppository base is Coca Butter or Theobroma oil.
Significance of Displacement Value:-
- It plays an important role in pharmacy and pharmaceutical calculations.
- These values are important when it comes to reconstituted powders.
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