Question

What do you mean by optical activity? What are the requirements
for a molecule to be optically active? Explain with example. [ for 10 Marks- i need answer in detail for 10 marks]​

Answer 1

Question

What do you mean by optical activity:

= Optical activity, the ability of a substance to rotate the plane of polarization of a beam of light that is passed through it. ... The rotation is assigned a positive value if it is clockwise with respect to an observer facing the light source, negative if counterclockwise.

Necessary required for optical activity:

• The compound must contain an asymmetrical carbon atom.
• The molecule must contain a chiral axis.
• The molecule must possess a chiral plane.
• The molecule does not possess any elements of symmetry. 

Explain with example:

For example, d-ethambutol treats tuberculosis, while l-ethambutol causes blindness. Optical activity is the interaction of these enantiomers with plane-polarized light.

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