What happens to golgi body in signet ring carcinoma?
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Signet Ring Cell Adenocarcinoma
Signet ring cell adenocarcinoma is defined as a tumor that is composed of at least 50% signet ring cells. For classification purposes, this feature supersedes the presence and amount of extracellular mucin. These tumors represent about 0.5% to 1.0% of all colorectal carcinomas.75–77 They are slightly more common in men (male-to-female ratio = 1.3 : 1) and occur at a younger age (mean age, 63.5 years).76 In some studies, more than 50% of signet ring cell adenocarcinomas were detected in individuals younger than 40 years of age.78 Signet ring cell carcinoma is also more common in ulcerative colitis; 30% of such tumors occur in patients with this form of IBD.79
Signet ring cell carcinomas develop with equal frequency in the right and left colon and thus constitute a greater fraction of all right-sided colonic tumors.75, 76 Synchronous tumors are found in 14% of patients.75 They are usually ulcerating, and about two thirds have an infiltrative gross appearance.75, 76 A linitis plastica growth pattern occurs in up to 20% of cases.76
Explanation:
Carcinoma is a type of cancer that starts in cells that make up the skin or the tissue lining organs, such as the liver or kidneys. Like other types of cancer, carcinomas are abnormal cells that divide without control. They are able to spread to other parts of the body, but don't always.