what happens when an amide is warmed with bromine and concentrated aqueous sodium hydroxide solution
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The amide given in the above question is converted into an amine, by reacting it with Bromine and concentrated solution of base.
This reaction is known as Hoffmann Hypobromamide Degradation. In this reaction, the carbonyl group is degraded to pass out as CO2 and react with NaOH. The alkyl group attached to the amide group undergoes Wolff rearrangement to form a bond with the nitrogen atom of the amide functional group.
This reaction is known as Hoffmann Hypobromamide Degradation. In this reaction, the carbonyl group is degraded to pass out as CO2 and react with NaOH. The alkyl group attached to the amide group undergoes Wolff rearrangement to form a bond with the nitrogen atom of the amide functional group.
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