Science, asked by meowteju9246, 1 year ago

What happens when phosphodiesterase is inhibited?

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Answered by Shahaninemat

Cyclic-AMP is broken down by an enzyme called cAMP-dependent phosphodiesterase (PDE). ... Inhibition of this enzyme prevents cAMP breakdown and thereby increases its intracellular concentration. This increases cardiac inotropy, chronotropy and dromotropy.

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