Question

What is a relation between mild liver pain and deficiency of probiotics?

Answer 1

Intestinal microbiota plays an also not been shown to prevent primary or secondary spontaneous bacterial peritonitis. Larger clinical studies are required before probiotics can be recommended as a treatment modality in liver diseases.

1. Introduction

Probiotics are defined by the World Health Organisation as live microorganisms that confer a health benefit on the host when administered in adequate amounts [1]. The concept of probiotics is not a novel entity. More than a century ago, Nobel Prize winner Eli Metchnikoff suggested that the long life of Bulgarian peasants was the result of their consumption of fermented milk products [2]. He went on to introduce in his diet sour milk fermented with the bacteria he called “Bulgarian Bacillus” and found his health benefited [3]. In actual fact, the practice of using probiotics in daily lives for health enrichment has been around for millenniums. Even in the ancient Greek and Roman empires, the use of cheese and fermented products was highly recommended [4]. Although the term “probiotic” was credited to Lilly and Stillwell [5] who in 1965 described probiotics as microorganisms that have effects on other microorganisms, the modern terminology and definition of probiotics was coined by Parker [6] who in 1974 defined probiotics as organisms and substances that have a beneficial effect on the host animal by contributing to its intestinal microbial balance. Consumption of modern era probiotics has been prevalent for decades even before the proper terminology was well established. As early as 1930, Shirota in Japan started to culture lactic acid bacteria (Lactobacillus casei strain Shirota) which he subsequently introduced into the market as Yakult in 1935 [7]. Today Yakult is marketed in 33 countries and 30 million bottles are consumed on a daily basis.