. What is acetylation and methylation of histone? How does it help in DNA replication and transcription?
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By doing this, the DNA is more accessible and leads to moretranscription factors being able to reach the DNA. Thus, acetylationof histones is known to increase the expression of genes throughtranscription activation. Deacetylation performed by HDAC molecules has the opposite effect.
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part a - Histone acetylation and methylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and methylation as part of gene regulation.
part b - Sorry, don't know
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