What is an active methylene group give two examples?
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Active methylene group is that group which has two -I or -R groups on its either side. Hence the hydrogens of this -CH2 group are extremely acidic. For example , considering acetyl acetone.
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An active methylene group is one where two electron-withdrawing groups are attached to it.
Examples are acetoacetic esters and cyanoacetic esters.
- We know carbon has four valencies.
- CH₂ group is called methylene group, we can see two valencies of carbon are not satisfied here.
- When the remaining valencies are satisfied by electron-withdrawing groups, then such methylene groups are called active methylene.
- When electron-withdrawing groups are attached to the carbon the hydrogens of the methylene group become more acidic.
- #SPJ2
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