what is aneuploidy? Give me some examples.
Answers
Answer:
Aneuploidy means an organism does not have the normal number of chromosomes. If there is 1 less chromosome, this is referred to as monosomic, abbreviated as 2n - 1. If there is 1 extra chromosome, this is called trisomic, abbreviated as 2n + 1. Examples of aneuploidy are trisomy 21 and XYY Klinefelter's Syndrome.
Answer:
Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46.[1][2] It does not include a difference of one or more complete sets of chromosomes. A cell with any number of complete chromosome sets is called a euploid cell.[1] An extra or missing chromosome is a common cause of genetic disorders, including some human birth defects. Some cancer cells also have abnormal numbers of chromosomes.[3][4] About 68% of human solid tumors are aneuploid.[4] Aneuploidy originates during cell division when the chromosomes do not separate properly between the two cells. Most cases of aneuploidy in the germline result in miscarriage and the most common extra autosomal chromosomes among live births are 21.
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