what is anomeric effect?
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In organic chemistry, the anomeric effect or Edward-Lemieux effect is a stereoelectronic effect that describes the tendency of heteroatomic substituents adjacent to a heteroatom within a cyclohexane ring to prefer the axial orientation instead of the less hindered equatorial orientation that would be expected from steric considerations.[1] This effect was originally observed in pyranose rings by J. T. Edward in 1955 when studying carbohydrate chemistry.
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