what is bone marrow transplant surgery?
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How does a blood or marrow transplant (BMT) work?
A blood or marrow transplant (BMT) replaces unhealthy blood-forming cells with healthy ones. Blood-forming cells (blood stem cells) are immature cells that grow into red blood cells, white blood cells and platelets. They’re found in the soft tissue inside your bones, called bone marrow. When they’re mature, they leave the marrow and enter the bloodstream.
Before transplant, you get chemotherapy (chemo) and sometimes radiation to destroy the diseased cells and marrow. Then, the healthy cells are given to you.
BMT is not surgery. The new cells go into your bloodstream through an intravenous (IV) catheter or tube. It’s just like getting blood or medicine through an IV. From there, the cells find their way into your marrow.. It can take months or years to recover from BMT
Where do the healthy cells come from?
Healthy blood-forming cells used in transplant can come from 3 sources:
Bone marrow: Spongy tissue inside of bones
Peripheral blood stem cells (PBSC): Blood-forming cells from the circulating blood
Cord blood: The blood collected from the umbilical cord and placenta after a baby is born
What are the different types of BMT?
There are 2 main types of transplant:
An autologous transplant uses your own blood-forming cells.
An allogeneic transplant uses blood-forming cells donated by someone else. The cells can come from:
A family member. This could be someone with closely matched human leukocyte antigens (HLA) like a sibling. Or this could be someone who matches half of your HLA, like a parent or child.
An unrelated adult donor or cord blood unit through the Be The Match Registry®
Other names for BMT
You might hear BMT called:
Allo (allogeneic) transplant
Auto (autologous) transplant
BMT – bone marrow transplant
Haplo – haploidentical, or half-matched, transplant
HCT – hematopoietic cell transplantSCT – stem cell transplant