What is cardiotoxic venom?
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Answers
Answer:
The effect of the purified cardiotoxic component of the venom from the Indian cobra snake (Naja nigricollis) on the subcellular function and structure of heart muscle cells was investigated. The concentration of toxin used ranged between 10 and 50 μg/ml. When added to microsomal fractions rich in sarcoplasmic reticulum 10 to 50 μg toxin/ml interfered with ability of these fractions to accumulate Ca2+ from an oxalatecontaining reaction mixture. This effect was accompanied by an inhibition of the Ca2+-activated ATPase enzyme. Ten, 25 and 50 μg toxin/ml caused the microsomes to release their previously bound Ca2+ at a relatively rapid rate, and accelerated the onset of this release process. Ten μg toxin/ml reduced the ability of isolated mitochondria to accumulate Ca2+ by approximately 50%; the ability of isolated fragments of the plasma membrane to accumulate Ca2+ was also reduced but to a lesser extent.
bhaarateey kobara saamp (naaja naigrikolis) ke jahar ke shuddh kaardiyotoksik ghatak ke up-koshikeey kaary aur hrday kee maansapeshiyon kee koshikaon kee sanrachana par prabhaav kee jaanch kee gaee. upayog kie gae vish kee saandrata 10 aur 50 mg / ml ke beech thee. jab saarkoplaajmik retikulam se bharapoor 10 se 50 maikrograam toksin/emel se bharapoor maikrosomal phraikshans mein milaaya jaata hai, to in phraikshans kee kshamata mein hastakshep hota hai, jisamen oksaalet yukt pratikriya mishran se cha2+ jama hota hai. yah prabhaav cha2+-sakriy atpasai enjaim ke nishedh ke saath tha. das, 25 aur 50 maikrograam toksin/emel ke kaaran maikrosom apekshaakrt tejee se apane pahale se bandhe cha2+ ko chhodate hain, aur is rileej prakriya kee shuruaat ko tej karate hain. das maikrograam toksin/emel prthak maitokondriya kee cha2+ jama karane kee kshamata ko lagabhag 50% kam kar deta hai; plaajma jhillee ke alag-alag tukadon kee cha2+ jama karane kee kshamata bhee kam ho gaee thee lekin kuchh had tak.
Explanation:
Answer:
Cardiotoxins are a confusing group of toxins, because the name is often used for certain snake venom components, even though in humans, they generally do not affect the heart significantly. ... It can cause cardiac arrhythmias or cardiac arrest.
Explanation:
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