What is cell destiny?
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R esearchers have cracked the code that guides immature human pancreatic cells to their destiny. ... They also observed mechanical force changes inside each cell that cued its development.
In this issue of Blood, Russo et al provide important insights on the effect of posttransplantation cyclophosphamide (PT-Cy) on natural killer (NK) cell recovery and function after haploidentical allogeneic stem cell transplantation (haploSCT). Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for a variety of hematologic malignancies, including acute leukemia and myeloproliferative disorders. For patients who lack an HLA-matched sibling donor, transplantation from a haploidentical donor is an emerging alternative.