Question

what is collagen fibres?❤​

Answer 1

Answer:

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Answer 2

★ Collagen fiber

• Collagen fiber is a fiber composition mainly containing collagen and amino acids such as glycine , proline and hydroxyproline . Collagen fiber is the most widely distributed and most abundant fiber among the three types of fibers. Widely distributed in various organs, the most abundant in the skin , sclera and tendons . Collagen fiber staining is mainly used for identification with muscle fibers.

Collagen fibers are leather major component, accounting for 95-98% of the total fiber mass of the dermis. Fresh white collagen fibers, so called white fibers. In HE stained specimens, collagen fibers are dyed pink, thicker, 0.5-20um in diameter, distributed in bundles, closely arranged, and interwoven into a net.

Collagen is the only protein that contains more hydroxyproline, so measuring the amount of hydroxyproline can determine the amount of collagen in the tissue. Collagen accounts for 30% of total body protein. The protein molecules of microfibrils that are aggregated into collagen are called procollagen molecules.

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★ Introduction

Collagen fiber (collagenous fiber) is the most abundant among the three kinds of fibers, and it is white and shiny when fresh, so it is also called white fiber. In HE stained slices, it is eosinophilic, with different thickness, 0.5 ~ 20um in diameter, wavy, branched and interwoven into a net, and the biochemical composition of collagen fibers is type I collagen . Collagen (collagen) is secreted by fibroblasts, polymerized into collagen fibrils outside the cell, and then a small amount of collagen fibers are synthesized. Under electron microscopy, collagen fibrils have a diameter of 20 ~ 200nm and show periodic stripes with alternating light and dark. The period of the stripes is about 64nm. The collagen fibers have high toughness and strong tensile strength.

→ Check tha attachment

Collagen fibers: dyed pink, bundle-like, most of the fibrils are unclear.

• During childhood, the collagen fibers of bones account for a large proportion, and osteoblasts are very active in producing bone. Therefore, children's bones are elastic and hard to break.