Question

What is cori's cycle?

Answer 1

It was proposed by Carl Ferdinand Cori and Gerty Theresa Cori (The husband wife duo), who eventually got the nobel prize with Houssay in 1947. This cycle occurs mainly in the muscles and the liver.
During glycolysis lactic acid is produced from pyruvic acid occuring in the muscles. The lactic acid is carried in the blood to the organ liver where 1/5th of the total lactic acid sim oxidised to water and carbon dioxide and 4/5th of the total in lactic acid is converted into the storage compound in liver, glycogen.
The glycogen releases glucose into the blood which is then reconverted to glycogen in the muscles. The cycle is repeated thereafter.
It is also applied to clear the oxygen debt when strenuous exercise is done above the limits of the body.

Answer 2

Answer is for Class 11 Biology Student.

Muscle Fatigue: Repeated activation of muscles can lead to accumulation of lactic acid due to anaerobic breakdown of glycogen in them, causing fatigue.

Cori Cycle also known as Lactic acid cycle refers to the metabolic pathway in which lactate produced by anaerobic glycolysis in the muscles moves to the liver and is converted to glucose, which then returns to the muscles and is metabolized back to lactate.

Note: Heart muscle fibers, kidney cells and liver cells can use lactic acid to produce ATP.

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