Question

What is directly responsible for increasing glomerular blood pressure?

Answer 1

Explanation:

Glomerular filtration is occurs due to the pressure gradient in the glomerulus. Increased blood volume and increased blood pressure will increase GFR. Constriction in the afferent arterioles going into the glomerulus and dilation of the efferent arterioles coming out of the glomerulus will decrease GFR.

Answer 2

Answer:

Assessment of GFR is essential to accurately diagnose kidney disease. GFR is difficult and impractical to measure directly with current methodologies, and estimates of GFR by serum creatinine and/or cystatin C are most accurate once GFR is <60ml/min/1.73m2, a point at which half of renal function is already lost.