Question

what is dissolution? what are the remedies to decrease it?​

Answer 1

Dissolution rate can be improved by reducing particle size (e.g., grinding the solid drug active ingredient or forming smaller particles), which increases surface area per unit of mass. With greater surface area, more of the compound is solubilized in the same time.

Answer 2

Dissolution:

• Dissolution means the mixing of a solute completely in the solvent.

• The dissolution depends on the size of the charged particle, the lesser the size the faster it will dissolve.

• A solute is the 'primary substance' that is dissolved in a liquid called the solvent.

• The substance which is present in less amount is solute and the one present in large amount is solvent.

• So, by reducing the size of the solute the dissolution process can be faster.

The remedies to decrease it:

• Greater surface areas of solids help them dissolve faster.

• Temperature increases dissolvability.

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