Question

What is false about tRNA? (1)It binds with an amino acid at it 3'end (2)It has double stranded regions (3)It has a codon at one end which recognizes the anticodon on messenger RNA (4)It looks like clover leaf in the two dimensional structure

Answer 1

Explanation:

All tRNAs have about 73 to 93 nucleotides that fold into four base-paired stems and three loops, a structure which looks like a clover leaf in two dimension and. it is "L" shaped in three-dimensional structure. The 3' end has CCA sequence. Attachment of an amino acid to the 3 adenosine yields an aminoacyl-tRNA. Transfer-RNA has 7-15% post-transcriptionally modified bases. Dihydrouridine (D) is nearly always found in the D-loop and ribothymidine (T) and pseudouridine in the T psi C loop. The D-loop serves as Aminoacyl synthetase recognition and binding loop while the T psi C loop binds the charged tRNA-amino acid to the ribosome. The anticodon loop has triplet at the tip which base pairs with the corresponding codon in mRNA. Thus, the correct answer is option A.

Answer 2

It has a double stranded region is false about tRNA.

Explanation:

• tRNA has anticodon loop that has bases complimentary to the code. It also has amino acid acceptor end which is at its 3' end opposite to the anticodon in tRNA which recognises the mRNA .
• tRNA molecule has a L shaped structure held together by hydrogen bond between bases in different parts of tRNA
• It has a characteristic clover leaf structure made up of D loop,T loop, variable loop and anticodon loop

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