Question

What is function of GLUT-4

Answer 1

GOOD MORNING FREIND

GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac)

The major cellular mechanism that diminishes blood glucose when carbohydrates are ingested is insulin-stimulated glucose transport into skeletal muscle. ... The principal glucose transporter protein that mediates this uptake is GLUT4, which plays a key role in regulating whole body glucose homeostasis

Answer 2

Answer:

Primarily prevalent in adipose tissues and striated muscle, GLUT4 is the insulin-regulated glucose transporter (skeletal and cardiac)

Explanation:

• GLUT4 allows the facilitated transport of circulatory glucose into muscle and fat cells down its concentration gradient at the cell surface.
• The liver's glucokinase and other tissues' hexokinases quickly phosphorylate glucose after it enters cells to create glucose-6-phosphate, which either enters glycolysis or is polymerized into glycogen.
• Because glucose-6-phosphate cannot diffuse back out of cells, the gradient of concentration for glucose to passively enter cells is kept constant.
• Muscular cells are prompted by muscle tension to move GLUT4 receptors to their surfaces.
• This is particularly evident in cardiac muscle, where continuous contraction speeds up GLUT4 translocation. However, greater skeletal muscular contraction is shown to a lesser amount.

For more information on glucose transporters:

Explaining secondary glucose transport proteins

https://brainly.in/question/40971863

Glucose metabolism release energy as?
https://brainly.in/question/26999583