Question

what is Gabriel phthalimide synthesis

Answer 1

Gabriel phthalimide synthesis is a convenient and important method for the synthesis of aliphatic primary amines. It includes the reaction between phthalimide with ethanolic potassium hydroxide forming potassium salt of phthalimide. This salt is then heated with alkyl halide, which is succeeded by alkaline hydrolysis to give in the resultant primary amine.

Answer 2

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⬇Answer ⬇

The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide. The reaction is named after the German chemist Siegmund Gabriel, who first posited the synthesis with the aid of his partner, James Dornbush.✔✔✔

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