What is genetic difference in between Klinefelter's Syndrome and Turner's Syndrome?
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Given below are the substantial points which differentiate both the syndromes:
Turner syndrome is the deletion of one of the sex chromosome (XO instead of XX) in the newborn, and so the effected person faces many difficulties in their physical appearance, as well as clinically, it occurs in the female. On the other hand, if a boy born with the extra X chromosome (XXY instead of XY), then he is said to be affected by Klinefelter syndrome.
Karyotype of the Turner syndrome is monosomy of sex chromosome (2n-1), where only one X chromosome is present, while in Klinefelter syndrome there is trisomy of sex chromosome (2n+1), in this XXY chromosome are present in males.
Turner syndrome and the Klinefelter syndrome are the rare cases where the earlier one occurs in 1 out of 2500 phenotypic female, while the latter one occurs in 1 in 1100 births.
There are many features of the Turner syndrome where are females are sterile, they have undeveloped breasts, even ovary are absent or poorly developed. Uterus, vagina, vulva present, but menstruation is absent. They even have webbed neck, short stature, cardiovascular problems, hearing impairment and has the physical appearance of female only.
In the case of Turner syndrome males are sterile, organs like testes, penis, vas deferens, seminal vesicle are small and undeveloped. The person is mentally disabled, have long limbs, thinner as well taller and show feminine characteristics, such as enlarged breasts, feminine pitched voice. Then too they physically appear as the male.
Turner syndrome is commonly treated with estrogen, growth hormones and replacement therapy while Klinefelter syndrome is treated with testosterone therapy
Turner syndrome is the deletion of one of the sex chromosome (XO instead of XX) in the newborn, and so the effected person faces many difficulties in their physical appearance, as well as clinically, it occurs in the female. On the other hand, if a boy born with the extra X chromosome (XXY instead of XY), then he is said to be affected by Klinefelter syndrome.
Karyotype of the Turner syndrome is monosomy of sex chromosome (2n-1), where only one X chromosome is present, while in Klinefelter syndrome there is trisomy of sex chromosome (2n+1), in this XXY chromosome are present in males.
Turner syndrome and the Klinefelter syndrome are the rare cases where the earlier one occurs in 1 out of 2500 phenotypic female, while the latter one occurs in 1 in 1100 births.
There are many features of the Turner syndrome where are females are sterile, they have undeveloped breasts, even ovary are absent or poorly developed. Uterus, vagina, vulva present, but menstruation is absent. They even have webbed neck, short stature, cardiovascular problems, hearing impairment and has the physical appearance of female only.
In the case of Turner syndrome males are sterile, organs like testes, penis, vas deferens, seminal vesicle are small and undeveloped. The person is mentally disabled, have long limbs, thinner as well taller and show feminine characteristics, such as enlarged breasts, feminine pitched voice. Then too they physically appear as the male.
Turner syndrome is commonly treated with estrogen, growth hormones and replacement therapy while Klinefelter syndrome is treated with testosterone therapy
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Answer:
Turner syndrome is the dysgenesis in the female gonads, while Klinefelter syndrome is the male hypogonadism. These can be explained by saying that both the terms are problems related to the sex chromosomes, as in the earlier one there is lacking of one of the sex chromosomes and so-called as monosomy (2n-1), while the latter consist of the extra sex chromosome and so-called as trisomy (2n+1).
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