what is hmg protine in (bangla)
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Answer:
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Explanation:
High mobility group proteins
High mobility group (HMG) proteins, the largest class of nonhistone proteins found in the nucleus, are often found in association with regions of active transcription in chromatin. These proteins have been reported to contain various post-translational modifications, including méthylation, acétylation, phosphorylation, ADP-ribosylation and glycosylation. Direct compositional analysis of purified HMG14 and HMG17 demonstrated the presence of N-acetylglucosamine, mannose, glucose, galactose and fucose. Further evidence for fucosylation was provided by the ability to bind the fucose-specific lectin UEA-I from Ulex europeus. The glycans from HMG proteins metabolically labeled with various monosaccharides were also resistant to release by mild alkali, thus suggesting N-linked glycans. In addition, a functional role for this glycosylation was suggested since the removal of the glycans by digestion with mixed glycosidases resulted in the loss of binding to nuclear matrix.