What is in general not a risk factor in gene therapy using adenoviruses?
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Explanation:
answer is = INSERTIONAL MUTAGENESIS
When adenoviruses infect a host cell, they introduce their DNA molecule into the host. The genetic material of the adenoviruses is not incorporated (transient) into the host cell's genetic material. The DNA molecule is left free in the nucleus of the host cell, and the instructions in this extra DNA molecule are transcribed just like any other gene. Because the virus is not inserted into the genome, there is no risk of insertional mutagenesis.
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