What is involved in formation of lysosomes
Answers
Answer:
Lysosomes are formed by Golgi apparatus, when a foreign material enters a cell. It also contains digestive enzymes which are made in ER. Thus ER and Golgi apparatus plays a key role in the formation of lysosomes
Answer:
Lysosomes occur by scratching from the trans-Golgi network layer, the Golgi complex region for the sorting of newly synthesized proteins, which can be designated for use in lysosomes, endosomes, or plasma membranes. Lysosomes then activate membrane vesicles obtained from one of three mechanisms: endocytosis, autophagocytosis and phagocytosis. In endocytosis, foreign macromolecules are taken to the cell to form membrane-bound vesicles called endosomes that interact with lysosomes. Autophagocytosis is a process in which old organs and cellular malfunctions are removed from the cell; they are covered by internal radiation and then in contact with the lysosomes. Phagocytosis is caused by specialized cells (e.g., macrophages) that include large foreign particles, such as dead cells or foreign invaders (e.g., viruses), and that point to lysosomal degradation. Most lysosomal digestion products, such as amino acids and nucleotides, revert to the cell for use in the formation of new cellular components.
Lysosome, is a subcellular organelle found in almost all types of eukaryotic cells (cells with a well-defined nucleus) and responsible for macromolecule digestion, adult stem cells, and microorganisms. Each lysosome is surrounded by an acid-retaining membrane inside the proton pump. Lysosomes contain many types of hydrolytic enzymes (acid hydrolases) that dissolve macromolecules such as nucleic acids, proteins, and polysaccharides. These enzymes work only inside the lysosome's acidic; their acid-dependent activity protects the cell from damage in the event of lysosomal leakage or inflammation, since the pH of the cell has little to do with alkali. Lysosomes were discovered by Christian René de Duve of the Belgian in the 1950s. (De Duve was awarded the 1974 Nobel Prize in Physiology or Medicine for his discovery of lysosomes and other organs known as peroxisomes.)