What is KLa? Describe factors affecting it?
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Measurements of kLa provide important information about a bioprocess or bioreactor. These determinations ensure that processing conditions are such that an adequate supply of oxygen is available for proliferation of cells. The kLa value can also be used to optimize control variables over the lifecycle of a bioprocess.
FACTORS AFFECTING THE VALUES OF MASS TRANSFER COEFFICIENTSIN FERMENTATION SYSTEMS
•Various operating parameters and physico-chemical properties of fermentation broth affects mass transfer rate, which in turn show effecton KLa
a.Factors affecting the value of kLa are:
1. Bubble size
2.Gas Hold-up
3.Gas Velocity
4.Type of gas sparger
5.Type of agitation
6. Power input to agitator
7.Temperature
8.Pressure
9. Antifoaming agents
10. Presence of cells
11. Surface active solutes
Hope it helped u mate...
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FACTORS AFFECTING THE VALUES OF MASS TRANSFER COEFFICIENTSIN FERMENTATION SYSTEMS
•Various operating parameters and physico-chemical properties of fermentation broth affects mass transfer rate, which in turn show effecton KLa
a.Factors affecting the value of kLa are:
1. Bubble size
2.Gas Hold-up
3.Gas Velocity
4.Type of gas sparger
5.Type of agitation
6. Power input to agitator
7.Temperature
8.Pressure
9. Antifoaming agents
10. Presence of cells
11. Surface active solutes
Hope it helped u mate...
PLZ MARK ME AS BRAINLIEST....
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