what is link reaction
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Pyruvate decarboxylation or pyruvate oxidation, also known as link reaction, is the conversion of pyruvate into acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex.Pyruvate oxidation is the step that connects glycolysis and the Krebs cycle. In glycolysis, a single glucose molecule (6 carbons) is split into 2 pyruvates (3 carbons each), hence link reaction occurs twice for each glucose molecule to produce a total of 2 acetyl-CoA molecules, which can then enter the Krebs cycle.
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