What is lock and key hypothesis of enzyme action?
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The Lock and Key Hypothesis
In 1894, German chemist Emil Fischer proposed the lock and key theory, which states that enzymes have a specific shape that directly correlates to the shape of the substrate. Basically, substrates fit into an enzyme the way a key fits into a lock
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The Lock and Key Hypothesis
Basically, substrates fit into an enzyme the way a key fits into a lock. If the substrate is not the correct shape, it won't fit into the enzyme, and no chemical reaction can occur. Only those substrates that exactly fit into the enzyme can be catalyzed.
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