What is lock and key model of enzyme action
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The specific action of an enzyme with a single substrate can be explained using a Lock and Key analogy first postulated in 1894 by Emil Fischer. In this analogy, the lock is the enzyme and the key is the substrate. Only the correctly sized key (substrate) fits into the key hole (active site) of the lock (enzyme).
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The lock and key model describes a situation in which the enzyme and the molecule that it acts on in a reaction, the substrate, fit together perfectly. For this system to work, the enzyme has an active site, which is like a keyhole for the substrate.
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