What is meant by Zaitsev reaction ? Mechanism and example.
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Saytzeff rule (or Zaitsev's rule, Saytzev rule) is an empirical rule for predicting the favoredalkene product(s) in elimination reactions. While at the University of Kazan, Russian chemist Alexander Zaitsev studied a variety of different elimination reactions and observed a general trend in the resulting alkenes. Based on this trend, Zaitsev stated, "The alkene formed in greatest amount is the one that corresponds to removal of the hydrogen from the β-carbon having the fewest hydrogen substituents." For example, when 2-iodobutane is treated with alcoholicpotassium hydroxide (KOH), 2-butene is the major product and 1-butene is the minor product.[1]
More generally, Zaitsev's rule predicts that in an elimination reaction, the most substituted product will be the most stable, and therefore the most favored. The rule makes no generalizations about the stereochemistry of the newly formed alkene, but only the regiochemistry of the elimination reaction. While effective at predicting the favored product for many elimination reactions, Zaitsev's rule is subject to many exceptions
More generally, Zaitsev's rule predicts that in an elimination reaction, the most substituted product will be the most stable, and therefore the most favored. The rule makes no generalizations about the stereochemistry of the newly formed alkene, but only the regiochemistry of the elimination reaction. While effective at predicting the favored product for many elimination reactions, Zaitsev's rule is subject to many exceptions
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2
Saytzeff rule (or Zaitsev's rule, Saytzev rule) is an empirical rule for predicting the favoredalkene product(s) in elimination reactions. While at the University of Kazan, Russian chemist Alexander Zaitsev studied a variety of different elimination reactions and observed a general trend in the resulting alkenes. Based on this trend, Zaitsev stated, "The alkene formed in greatest amount is the one that corresponds to removal of the hydrogen from the β-carbon having the fewest hydrogen substituents." For example, when 2-iodobutane is treated with alcoholicpotassium hydroxide (KOH), 2-butene is the major product and 1-butene is the minor product.[1]
More generally, Zaitsev's rule predicts that in an elimination reaction, the most substituted product will be the most stable, and therefore the most favored. The rule makes no generalizations about the stereochemistry of the newly formed alkene, but only the regiochemistry of the elimination reaction. While effective at predicting the favored product for many elimination reactions, Zaitsev's rule is subject to many exceptions
More generally, Zaitsev's rule predicts that in an elimination reaction, the most substituted product will be the most stable, and therefore the most favored. The rule makes no generalizations about the stereochemistry of the newly formed alkene, but only the regiochemistry of the elimination reaction. While effective at predicting the favored product for many elimination reactions, Zaitsev's rule is subject to many exceptions
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