Biology, asked by abhishek992255, 5 months ago

what is mechanism of chloroquine synthesis

Answers

Answered by AbhiThakur07

Explanation:

The mechanism of its action is not completely clear, although there are several hypotheses explaining its antimalarial activity. Chloroquine and its analogs inhibit synthesis of nucleic acids of the parasite by affecting the matrix function of DNA.

Answered by XxItzqueenxX00

Answer:

The major action of chloroquine is to inhibit the formation of hemozoin (Hz) from the heme released by the digestion of hemoglobin (Hb). The free heme then lyses membranes and leads to parasite death. Chloroquine resistance is due to a decreased accumulation of chloroquine in the food vacuole.

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