What is medicated permeability and types of medicated permeability?
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Hydrogel dressings are being popularized for wound care management because of their softness, tissue compatibility, and ability to enhance wound healing process. PVP-CMC and PVP-CMC-BA hydrogels were prepared using polyvinylpyrrolidone (PVP), sodium-carboxymethylcellulose (CMC), polyethyleneglycol (PEG), agar, glycerine and without/with boric acid (BA).
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The permeability of a membrane for the molecules totally depends on the transport proteins fixed in the membrane. This phenomenon is called mediated permeability.
Two molecules of same size, shape, structure and lipid solubility can show different permeability through a common membrane. Some moves faster and some slower depending upon the transporting molecule inside the membrane that allows the passing of molecules. This is called mediated permeability.
Examples are: water mediated permeability and CFTR mediated chloride permeability.
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