Question

What is mutation? what is its significance? explain with the help of example?

Answer 1

A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic message carried by that gene.Mutation plays an important role in evolution. The ultimate source of all genetic variation is mutation. Mutation is important as the first step of evolution because it creates a new DNA sequence for a particular gene, creating a new allele.For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced. change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations.