what is nucleophilic center
Answers
Nucleophile means "nucleus loving" which describes the tendency of an electron rich species to be attracted to the positive nuclear charge of an electron poor species, the electrophile . ... The more available the electrons, the more nucleophilic the system. Hence the first step should be to locate the nucleophilic center.
please mark it as a brainlist please plz plz plz plz plz plz plz plz plz plz plz plz plz plz plz plz plz plz
In organic and inorganic chemistry, nucleophilic substitution is a fundamental class of reactions in which an electron rich nucleophile selectively bonds with or attacks the positive or partially positive charge of an atom or a group of atoms to replace a leaving group; the positive or partially positive atom is referred to as an electrophile. The whole molecular entity of which the electrophile and the leaving group are part is usually called the substrate. The nucleophile essentially attempts to replace the leaving group as the primary substituent in the reaction itself, as a part of another molecule.
The most general form of the reaction may be given as the following:
Nuc: + R-LG → R-Nuc + LG:
The electron pair (:) from the nucleophile(Nuc) attacks the substrate (R-LG) forming a new bond, while the leaving group (LG) departs with an electron pair. The principal product in this case is R-Nuc. The nucleophile may be electrically neutral or negatively charged, whereas the substrate is typically neutral or positively charged.
An example of nucleophilic substitution is the hydrolysis of an alkyl bromide, R-Br, under basic conditions, where the attacking nucleophile is the OH− and the leaving group is Br−.
R-Br + OH− → R-OH + Br−
Nucleophilic substitution reactions are commonplace in organic chemistry, and they can be broadly categorised as taking place at a saturated aliphatic carbon or at (less often) an aromatic or other unsaturated carbon centre.
