What is oxidative deamination? Explain with example.
Answers
Oxidative deamination is an oxidation reaction, which occurs under aerobic conditions in most tissues, and occurs largely on glutamic acid residues since glutamic acid is the end product of many transamination reactions. Oxidative deamination is also known to cause the loss of the amino groups of lysine and has been identified in oxidized proteins.
While enzymatic forms of this reaction are important in maintaining nitrogen balance, oxidative deamination can also occur as an enzymatic reaction, where the deamination of lysine can be catalyzed by the enzyme lysine oxidase. Oxidative deamination is also the first step in the breakdown of norleucine and structurally related non-standard amino acids such as norvaline, beta-methylnorleucine, and homoisoleucine.
For example, oxidative deamination of norleucine would yield ketocaproic acid and ammonia.
PLZ MARK IT AS A BRAINLIEST
HOPE THIS HELPS YOU