Question

what is phbv ? how it is synthesized? give one example

Answer 1

Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) , commonly known as PHBV, is a polyhydroxyalkanoate-type polymer. It is biodegradable, nontoxic, biocompatible plastic produced 
it can be produced by the recombinant Escherichia coli strains


PHBV is synthesized by bacteria as storage compounds under growth limiting conditions. It can be produced from glucose and propionate by the recombinant Escherichia coli strains. Many other bacteria like Paracoccus denitrificans and Ralstonia eutropha are also capable of producing it. It can also be synthesized from genetically engineered plants. PHBV is a copolymer of 3-hydroxybutanoic acid and 3-hydroxypentanoic acid.PHBV may also be synthesized from butyrolactone and valerolactone in the presence of oligomeric aluminoxane as catalyst


PHBV find its applications in controlled release of drugs, medical implants and repairs, specialty packaging, orthopedic devices and manufacturing bottles for consumer goods

Answer 2

PHBV stands for poly-β-hydroxy butyrate co-β-hydroxy valerate. It is the monomer of 3-hydroxybutanoic acid and 3-hydroxypentanoic acid are joined by ester bonds. The backbone of the polymer is made up of Carbon and Oxygen atoms. The properties of PHBV depends on the ratio of these two monomers in it.
In the normal PHBV production process in bacteria, propionate is added as the direct precursor of propionyl-CoA. Therefore, most attempts aimed at producing PHBV copolymer or increasing the 3HV fraction in the copolymer were based on the strategies of propionate utilization