Question

what is polarity with reference to double strand dna

Answer 1

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The double-stranded has no polarity. This observation by Francis Crick, based on Rosalind Franklin's work, was one of the crucial steps in working out the structure of DNA. Since each strand has a 3′OH end and a 5′PO4 end, the only way the molecule has no polarityis if the two strands are antiparallel.

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Answer 2

polarity create in DNA fragments due to the hydrogen bases, like as purine or pyramidine.
because phosphate group form bond with dioxyribose sugar through an Easter bond between its one of it's negatively charged oxygenand 5' OH of the sugar.