Question

What is reference point and frame.

Answer 1

Frame--In molecular biology, a reading frame is a way of dividing the sequence of nucleotides in a nucleic acid (DNA or RNA) molecule into a set of consecutive, non-overlapping triplets

sorry i don't know about reference

Answer 2

physics, a frame of reference (or reference frame) consists of an abstract coordinate system and the set of physical reference points that uniquely fix (locate and orient) the coordinate system and standardize measurements. In n dimensions, n + 1 reference points are sufficient to fully define a reference frame.