Question

what is sequence of duplex in dna?​

Answer 1

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Duplex sequencing is a library preparation and analysis method for next-generation sequencing (NGS) platforms that employs random tagging of double stranded DNA to detect mutations with higher accuracy and lower error rate. This method uses degenerate molecular tags in addition to sequencing adapters to recognize reads originating from each strand of DNA. The generated sequencing reads then will be analyzed using two methods: single strand consensus sequences (SSCSs) and Duplex consensus sequences (DCSs) assembly. Duplex sequencing theoretically can detect mutations with frequencies as low as 5 x 10−8 that is more than 10,000 fold higher in accuracy compared to the conventional next-generation sequencing methods.
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Answer 2

Hello friend......

Here's ur answer .... ..

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The duplex sequencing method addresses this problem by taking advantage of complementary nature of two strands of DNA and confirming only variants that are present in both strands of DNA.✔️✔️

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Hope it helped u....☺️☺️